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Choosing A Dermal Filler : Hyaluronic Acid or Collagen Biostimulator -What’s best?


In recent years, dermal fillers have become a popular means of addressing volume loss and contour defects resulting from ageing, disease or even trauma, and the most widely used are the ones based on hyaluronic acid (HA) gels. However, non-permanent collagen-stimulating dermal fillers have become an increasingly important and popular treatment in medical aesthetics, targeting the entire face to restore shape for a more harmonious and natural effect. Today, let me share about what the difference is between HA and Collagen Biostimulator in order for you to have a better understanding.

Hyaluronic Acid vs Collagen Biostimulator -Their Respective Roles

Hyaluronic Acid (HA), a hyaluronan, is a non-sulfated glycosaminoglycan (GAG), a polysaccharide that occurs naturally in the skin and throughout body’s connective tissue.

  • HA has the capacity to bind water up to 1000 times its mass.

  • Responsible for that plump which key to skin moisture.

  • Functions as a humectant and holds water molecules to keep your skin hydrated.

  • Creates lubrication and volume with a pliable framework that suspends and adheres to collagen and elastin.

Before knowing the collagen-biostimulator, do you really know what collagen is? Let me tell you a little bit more.


Collagen is a natural protein that is organized in the matrix of our body as well as skin. It imparts durability and resilience to our skin. The matrix, or scaffold provides structural support for the skin. Collagen stimulators work by energising the body’s skin healing abilities:

  • Induce a controlled inflammatory response, triggers the body’s natural self-healing and self-regenerative processes

  • Stimulate the production of collagen and other essential proteins.

  • Improve elasticity, firmness and diminish signs of ageing, such as fine lines, wrinkles and sagging.

Know a little more

Collagen stimulators are commonly split into :

  • Poly-L-lactic acid (PLLA)

  • Calcium Hydroxyapatite (CaHA): Radiesse

  • Polyaprolactite (PCL)

  • Polynucleotides (PN): Rejuran, Plinest, Newest

REMEMBER, Hyaluronic Acid and Collagen both decrease as you become older. Ageing, along with external factors such as UV rays and inflammation, reduces both HA and collagen. This is why skin becomes thinner, sagging, lax, less hydrated and dull.


Treatment option for different age groups.

Both young and old can suffer from dry and dehydrated skin due to environmental factors. Thus, HA filler is the option to deposit ‘water reservoirs’ into your skin and make it looks more glowy and dewy. Since the collagen in our skin is very stable, it takes about 20 years for it to be replaced, that’s why young people do not have much noticeable signs of collagen loss such as sagging skin. A collagen-stimulator can therefore be more suitable for those who have reached their 40s, or those with genetically predetermined sagging skin at a younger chronological age. So, which is better? Clearly, it depends on many aspects and the actual problem you want to solve.

How long do the results last?

Generally, collagen biostimulators tend to provide longer results than, for example, other more common injectables like crosslinked hyaluronic acid (HA) dermal fillers, as they stimulate collagen production, which gradually improves the skin quality over time. Therefore, results can last for 12 months or even years, making it a more desirable option for individuals seeking lasting improvements. For Hyaluronic Acid, it provides instant result, in which you can see a ’fuller’ effect immediately. However, how long does the result last? Generally, it can last for 6-9 months depending on the concentration and viscosity, but not to forget the result depends on the area of treatment as well.


Available top-notched FDA-approved products in Dream Clinic

1. Hyaluronic Acid Dermal Filler :

  • Juvederm collection (USA)

  • Restylane (USA)

  • Teosyal RHA /Redensity II (Switzerland)

  • Belotero (Germany)

  • Aliaxin (Italy)

2. Collagen-Biostimulator

  • Radiesse (Germany)

  • Rejuran (Korea)

  • Plinest/Newest (Italy)

  • Profhilo (Italy ) -> HA Biostimulator

Nutshell

The truth is both HA filler and collagen-biostimulator play their respective role in skin rejuvenation to provide youthful-looking and volumized skin. Neither can do without the other. Daily skincare routine is of utmost importance too. Thus, what are you still waiting for? Hurry on, do visit us at Dream Clinic for a personalised aesthetic assessment and perfect your own beauty.

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