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Plinest Treatment: The Secret to Youthful, Radiant Skin


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Are you struggling with aging skin, large pores, acne scars, or hyperpigmentation, and longing for a solution that doesn't involve invasive procedures?


Look no further than Plinest, a revolutionary aesthetic treatment that is changing the game in skin rejuvenation. With a simple injection, it can unlock your skin's potential and restore your youthful, radiant appearance.


Join us as we explore the science behind Plinest and discover how this treatment can transform your skincare routine, bringing you closer to the perfect skin you've always dreamed of.


What is Plinest Treatment?


Plinest treatment

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Plinest is a skin booster treatment that rejuvenates your skin from within.


Developed by Mastelli, an Italian company with over 70 years of research in the field, Plinest combines the power of nature with advanced biotechnology to work at a deeper level, stimulating your skin's natural regenerative processes


Essentially, Plinest acts as a "wake-up call" for your skin cells, asking them to behave like younger, healthier cells.


What is Plinest Made Of?


The key ingredient of Plinest is PN-HPT™


This unique component combines polynucleotides (PN) - DNA fragments extracted from Italian trout gonads - with the patented DNA extraction and purification technology “Highly Purified Technology” (HPT™) developed by Mastelli in Italy.


Now, a question may arise: “Why use fish DNA? ” 


The answer lies in the properties of these specific polynucleotides. They can stimulate cellular regeneration and promote collagen production in human skin


They're also biocompatible, meaning they can work harmoniously with our body's natural processes, resulting in less irritation, minimal residue, and fewer complications for long-term use.


To further enhance Plinest's effectiveness, other skin-loving ingredients may be added to Plinest:


This unique combination of ingredients makes Plinest a comprehensive solution for various skin issues, setting it apart as a standout in the world of aesthetic treatments.


How Does Plinest Work?


A woman washing face

Photo by Freepik


When injected into the skin, Plinest sets off a cascade of regenerative processes:


  1. Bio-Revitalization: Stimulates the growth of fibroblast cells and enhances the performance of existing fibroblast, thus boosting collagen production.


  2. Collagen Regeneration: Increases the synthesis of type I and III collagen, which are crucial for maintaining skin firmness and elasticity.


  3. Tissue Repair: Promotes the healing of aging and damaged tissue, resulting in a more even skin surface. 


  4. Hydration Boost: Improves skin hydration and elasticity, providing a natural skin-lifting effect and leading to a more supple and youthful appearance.


  5. Extracellular Matrix Proliferation: Encourages the growth of the skin's extracellular matrix, which helps flatten wrinkles and acne scars, as well as minimize large pores.


 

Did you know that laser treatments can also rejuvenate your skin? 

Check out our article on Fotona Laser to discover more about this effective method for achieving youthful, glowing skin!

 

What are the Incredible Benefits of Plinest?


Plinest offers a range of products designed to address various skin care needs, including Plinest, Plinest Fast, and Plinest Newest.


Plinest, the original formulation, is ideal for treating the face, décolleté, and hands. Décolleté is the area of your chest and neck that a low-cut top would expose.


Its benefits include:

  • Providing a comprehensive bio-revitalization to combat skin aging

  • Softening and flattening your acne scars, fine lines, and wrinkles 

  • Minimizing skin pores

  • Enhancing skin hydration and elasticity

  • Improving skin radiance for a youthful glow


As for Plinest Fast, it is specifically formulated for more delicate areas such as the periocular region. However, it also works well in treating the glabella, forehead, neck, décolleté, and hands. 


It is efficient in:

  • Lightening dark circles

  • Reviving tired-looking eyes

  • Serving as a preparation and aftercare for blepharoplasty procedures

  • Reducing superficial wrinkles and fine lines in sensitive skin areas


Lastly, Plinest Newest is an advanced variation incorporating hyaluronic acid and mannitol into its formula, further enhancing skin hydration and elasticity. Like the original Plinest, it's suitable for the face, décolleté, and hands. 


Plinest Newest offers similar benefits to the original formulation:

  • Providing total bio-revitalization to reverse skin aging

  • Softening and flattening your acne scars, fine lines, and wrinkles

  • Minimizing skin pores

  • Improving skin hydration and elasticity

  • Enhancing skin radiance for a youthful glow


With these three specialized products, the Plinest line offers comprehensive solutions to different skincare problems, helping you achieve healthier and younger skin.


Ready to explore how Plinest can transform your skin? Visit Dream Clinic today for a personalized consultation with our expert aesthetic professionals! 


Why Should You Consider Plinest Treatments?


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If you're wondering whether Plinest treatment is right for you, the answer is a resounding yes


Here's why Plinest is an essential addition to your beauty regimen:


  1. It works from within

    Unlike topical products that work on the surface, Plinest stimulates skin rejuvenation from the inside out, complementing your existing skincare products.


  2. It enhances skincare product absorption

    By improving skin health at a cellular level, Plinest allows your skin to absorb other skincare products more effectively.


  3. It provides a strong foundation for your skin

    By promoting collagen production and overall skin health, Plinest creates a better 'canvas' for the rest of your skincare and makeup products.


  4. It offers preventative benefits

    Regular Plinest treatments can help prevent aging signs, making it a valuable addition to your anti-aging skincare routine.


  5. It is versatile

    Plinest can be used on various body areas, making it a versatile addition to your beauty arsenal.


 

Similar to Plinest, Profhilo works as an internal workout for your skin, smoothing and hydrating it while stimulating its long-term repair processes. 

To discover how this treatment could complement your skincare regimen, check out our detailed article on Profhilo!

 

What is the Procedure of Plinest Treatment?


The Plinest treatment procedure is relatively straightforward and minimally invasive. Here's what you can expect:


Before The Treatment

  • You will have a consultation with a qualified practitioner to discuss your concerns and goals.

  • Your skin will be assessed to determine the best treatment plan.

  • Your practitioner may recommend some pre-treatment care (e.g., avoiding certain medications or supplements) to enhance your treatment results.


During The Treatment

  • Your treatment area will be cleaned and numbed with a topical anesthetic before the treatment starts.

  • Then, Plinest is injected into your skin using fine needles.

  • The procedure typically takes about 30-45 minutes, depending on the treated area.

  • You may feel a slight pinching sensation during the injections, but most patients find the procedure comfortable.


After The Treatment

  • You may experience some redness, swelling, or bruising at the injection sites, but this typically subsides within a day or two.

  • You will be given aftercare instructions to follow, which may include:

    • Avoid direct sun exposure for 24 hours.

    • Do not use active skincare products (e.g., AHA, retinol, vitamin C) the night after treatment.

    • Do not engage in any activities that generate heat for 48 hours, such as strenuous exercise, saunas, spas, and steam rooms.

    • Do not massage the treatment area unless instructed to do so.


Is Plinest Better Than Rejuran?


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Similar to Plinest, Rejuran is also an injectable polynucleotide extract known for its effectiveness in skin rejuvenation. 


However, the choice between Plinest and Rejuran ultimately depends on individual needs, preferences, and skin conditions. 


To help with this decision, we have compared the key features of both treatments:

  1. Source

    Plinest is derived from the polynucleotides of Italian trout gonads, whilst Rejuran is extracted from the polynucleotides of wild salmon gonads in South Korea.  


  2. Technology

    Plinest uses Mastelli's patented Highly Purified Technology (HPT™), while Rejuran utilizes the DNA Fragments Optimizing Technology (DOT™). 


    Both technologies ensure high DNA purification standards.


  3. Bio-compatibility

    Plinest's HPT™ process results in a more biocompatible product, potentially causing less swelling and irritation than Rejuran. 


    This could be particularly beneficial for sensitive areas or patients with reactive skin.


  4. Effectiveness

    Noticeable improvements in skin tone, texture, hydration, and elasticity can be seen within weeks for both treatments, with optimal outcomes achieved after completing the full course.


    However, some users report that Plinest provides more comprehensive results, addressing a wider range of skin concerns.


  5. Safety

    Both Plinest and Rejuran are approved by the FDA (Food and Drug Administration) in the U.S. and certified by the CE (Conformité Européenne) in the European Union (EU).


    This indicates that both treatments are safe and compatible for use with the human body. 


  6. Comfort and Recovery

    For both treatments, patients can expect minor discomfort and light bruising or swelling post-injection, typically lasting a few days.


  7. Contraindications

    Both treatments should be avoided by pregnant women, vegetarians, vegans, or those with allergies to fish or seafood.


In sum, both treatments have good safety records and high satisfaction rates in the market. Hence, it's best to consult a qualified practitioner to determine which treatment suits your specific skin goals and concerns.


What are the Expected Results of Plinest? 


Plinest treatment delivers remarkable, visible results.


Most patients start to see improvements in their skin within a few weeks of their first treatment, with results continuing to improve over time.


Here is a photo of one of our patients before and after receiving Plinest treatment:


Before and after Plinest treatment outcome

Your Skin Deserves Plinest: Book Your Consultation at Dream Clinic Today!

As explored in this article, Plinest offers a revolutionary approach to skin rejuvenation, promising natural-looking results that enhance your unique beauty. 


At Dream Clinic, we're committed to bringing you the latest in premium aesthetic treatments with a focus on great service, top efficacy, and the highest regard for safety. This has earned us recognition as one of the top 3 aesthetic clinics in Penang within just a year of operation.


But our excellence continues beyond there. Dr. Jesse, the founder of Dream Clinic, holds the esteemed position of Honorable Trainer for Plinest in Malaysia, further solidifying our expertise in this groundbreaking treatment.


So, why merely dream about perfect skin when you can make it a reality? 


Visit us today to discover how we can help you achieve your aesthetic goals safely and effectively, not just with Plinest but with our full range of state-of-the-art aesthetic treatments!


FAQ


How many sessions will I need with Plinest?

The number of Plinest sessions you will need depends on your skin conditions and goals. 


At Dream Clinic, we offer 3 products in the Plinest line: Plinest, Plinest Fast, and Plinest Newest, with each of them following a similar treatment protocol:

  • Start-Up: 1 session every 14 or 21 days for a total of 3 sessions

  • Maintenance: 1 session every 6 to 9 months


For optimal results, we typically recommend a series of treatments spaced about 3-4 weeks apart. After completing the initial series, you may benefit from maintenance treatments every 4-6 months to preserve and enhance the effects.


However, everyone's skin is unique. Your treatment plan may need to be adjusted based on your specific needs and response to the treatment. 


To determine the best Plinest treatment plan for you, consult with our skin care professionals today. We can provide a personalized assessment and recommend the most effective course of treatment to help you achieve your skincare goals.


How long does it take for Plinest to work?

Some improvements may be noticeable immediately after treatment, such as increased hydration and a subtle "glow". However, the full effects of Plinest develop gradually over time. 


Most patients report significant improvements in skin quality, texture, and firmness within 4-6 weeks after their first treatment, with results continuing to improve over the following months.


For more information on the additional benefits of Plinest, please refer to this section.


How long does Plinest last?

The effects of Plinest can last anywhere from 6 to 12 months, depending on factors such as age, lifestyle, and skin condition. To maintain optimal results, follow-up treatments are recommended every 4-6 months.


Is Plinest treatment painful?

Most patients report minimal discomfort during Plinest treatment, as the procedure involves injections with fine needles, which may cause a slight pinching sensation. 


To enhance comfort, a topical numbing cream is typically applied before the treatment.

Hence, the discomfort is generally well-tolerated and momentary, with many patients describing it as less painful than other injectable treatments.


For more information on the procedures of Plinest treatment, please refer to this section.


Is there any downtime or side effects for Plinest?

Plinest treatments typically have minimal downtime. 


Some patients may experience mild redness, bruising, or swelling at the injection sites, which usually subsides within 24-48 hours. These effects are generally mild and do not interfere with daily activities. 


More severe side effects are rare, but as with any aesthetic treatment, they will be discussed during your consultation.


Can I combine Plinest with other treatments?

Yes, Plinest can be combined with other aesthetic treatments to enhance overall results, such as HIFU, dermal fillers, botulinum toxin injections, and various laser therapies.


However, the timing and combination of treatments can only be determined by a qualified practitioner to ensure safety and optimal outcomes.


To explore how Plinest can be effectively combined with other aesthetic treatments to achieve your skincare goals, schedule your consultation at Dream Clinic today!


group-photo-of-aesthetic-skin-specialist-in-dream-clinic

References

  1. Cavallini, M., Bartoletti, E., Maioli, L., Massirone, A., Pia Palmieri, I., Papagni, M., ... & Trocchi, G. (2020). Consensus report on the use of PN‐HPT™(Polynucleotides Highly Purified Technology) in aesthetic medicine. Journal of Cosmetic Dermatology, 20(5), 922-928. doi:10.1111/jocd.13679


  2. Colangelo, M.T., Govoni, P., Belletti, S., Squadrito, F., Guizzardi, S., & Galli, C. (2021). Polynucleotide biogel enhances tissue repair, matrix deposition and organization. Journal of Biological Regulators and Homeostatic Agents, 35(1), 355–362. https://doi.org/10.23812/20-320-L   


  3. Khor, S.M. (2024, June 4). Choosing The Right Moisturiser. Dream Clinic. https://www.dreamclinic.my/post/choosing-the-right-moisturiser


  4. Lim, T. S., Liew, S., Tee, X. J., Chong, I., Lo, F. J., Ho, M. J., Ong, K., & Cavallini, M. (2024). Polynucleotides HPT for Asian skin regeneration and rejuvenation. Clinical, Cosmetic and Investigational Dermatology, 17, 417-431. https://doi.org/10.2147/CCID.S437942 


  5. Taieb, M., Gay, C., Sebban, S., & Secnazi, P. (2012). Hyaluronic acid plus mannitol treatment for improved skin hydration and elasticity. Journal of Cosmetic Dermatology, 11(2), 87-92. doi:10.1111/j.1473-2165.2012.00608

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